How Is It Applied?

Colo-Check analysis is an optimized process that progresses step by step

Colo-Check is an analysis process in which every step, from sample collection to result reporting, is planned in a controlled, highly sensitive way suitable for molecular diagnostics.

Molecular diagnostic laboratory
Approximately 7-8 hours of laboratory process

Sample quality and DNA integrity are key factors that directly affect test performance.

01 Sample collection and acceptance
02 DNA-based molecular analysis
03 Result evaluation and referral

Diagnostic workflow

Step-by-step Colo-Check analysis

The process consists of proper sample collection, transportation to the laboratory under suitable conditions, preservation of genetic material, molecular analysis, and result interpretation.

1

Collection of patient samples

Stool and/or serum samples are collected from the patient for the test. For the highest accuracy rate, it is recommended that stool and serum samples collected from the same patient be evaluated together.

2

Sample acceptance and quality control

It is checked whether the samples have arrived under suitable conditions. Sample quality is critical for DNA integrity and analysis reliability.

3

Preparation of genetic material

DNA isolation is performed from the samples in the laboratory environment. The pre-analysis process is carried out in a way that preserves molecular diagnostic sensitivity.

4

Analysis of epigenetic targets

Colo-Check works through gene panels that target cancer-specific DNA methylation patterns. Stool and serum samples can be analyzed separately or together.

5

Evaluation of results

The obtained molecular findings are evaluated. Patients with positive results should be referred for colonoscopy for clinical confirmation.

Sample quality

The success of the test begins with sample integrity

In the Colo-Check process, collecting, preserving, and delivering the sample to the laboratory correctly directly affects analysis performance.

Stool sample It is one of the main sample types used to screen epigenetic markers.
Serum sample It provides supportive and complementary analysis capability in the dual matrix approach.
Cross-evaluation When stool and serum data are evaluated together, diagnostic performance is strengthened.
Laboratory sample preparation process

Patient experience

Non-invasive and patient-friendly application approach

Compared to the invasive nature of colonoscopy, the need for sedation, and challenging preparation processes, Colo-Check aims to provide a more comfortable screening experience.

01

Does not require colonoscopy preparation

It offers a more comfortable sampling approach independent of challenging bowel preparation and sedation processes.

02

Supports patient compliance

Thanks to its non-invasive structure, it may help increase participation in the screening process.

03

Referral in case of a positive result

Patients with a positive test result are referred for colonoscopy for clinical confirmation.

Clinical note Colo-Check is not a definitive diagnostic method that replaces colonoscopy. Positive results must be confirmed through specialist physician evaluation and colonoscopy.

Application process

Controlled, fast, and molecular-based analysis

Colo-Check offers an optimized molecular diagnostic process carried out in an advanced technology laboratory environment, from sample acceptance to reporting.

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